Warning: include_once(D:\data\cometsys): failed to open stream: No such file or directory in D:\data\cometsystem\www\index.php on line 2

Warning: include_once(): Failed opening '_inc/initialize.php' for inclusion (include_path='.;C:\php\pear') in D:\data\cometsystem\www\index.php on line 2

Fatal error: Uncaught Error: Call to a member function execute() on null in D:\data\cometsystem\www\index.php:41
Stack trace:
#0 {main}
  thrown in D:\data\cometsystem\www\index.php on line 41